Rahul Dutta

My current research interest spans a wide range of areas, from investigating the impact of hypoxia-induced polarization of macrophages on endometriosis progression to exploring selective targeting of the M2 macrophage population using proapoptotic m2pep KLA fusion peptides. We employ physiologically relevant in vitro models, such as mice endometrial stromal cell culture (ESCC) and macrophage culture, as well as human endometrial stromal cell culture, to decipher the intricate interactions underlying this complex condition.

Beyond our focus on the molecular mechanisms of endometriosis, we are passionate about advancing clinical approaches to improve patient outcomes. Our lab is pioneering a multispectral optoacoustic and ultrasound imaging-based smart needle guiding technology for oocyte retrieval during in-vitro fertilization (IVF) procedures in endometriotic patients. By harnessing the power of AI and state-of-the-art imaging techniques, our goal is to automate the oocyte retrieval process, minimize risk factors, and reduce potential contamination, ultimately enhancing assisted reproductive technologies (ART).

For contact: rahul.dutta@manipal.edu

                    Megha M Anchan

I’m Megha M Anchan, pursuing Ph. D in reproductive science with over six years of research experience in academia as well as industry. With a background in cell and molecular biology, my current research focuses on understanding "Endometriosis". My work focuses on establishing a physiologically relevant mouse model to decode the disease, while simultaneously exploring strategies to manage it, hoping what we understand in the laboratory will ultimately lead to better treatment options.

My aim is to combine basic research with real-world applications with each experiment, dataset, and discovery contributing to a greater understanding of the condition, bringing us one step closer to improving patient care.

In my free time, I enjoy quiet hobbies like reading, journaling, and experimenting with new recipes.

For contact: megha.kmcmpl2022@learner.manipal.edu

                                         Atharvaraj Hande

Hello. I am Atharvaraj Hande. I have an academic background in microbiology from Charotar University of Science and Technology, Gujarat. Moreover, I have experience in cell culture techniques, molecular biology, and animal handling. Considering these skills, I am working on the silent yet concerning gynecological disorder, i.e., endometriosis, from a fibrosis perspective.

Motivated by the challenges in curing fibrosis; my goal is to find a curable drug for women suffering from such a debilitating condition. My work will take a translational approach aiming to create meaningful societal impact.

In my leisure time, I enjoy drinking tea, discussing scientific and societal topics, also playing and watching basketball.

For contact: atharvaraj.kmcmpl2023@learner.manipal.edu

                                  Samruddhi Deshpande

Hello, I am Samruddhi Deshpande, a PhD scholar with an interest in scientific discovery and women's health. My academic background was in biotechnology, and in the process, I built a strong foundation in molecular biology, cell culture techniques, and advanced lab techniques. Currently, my research focuses on chronic pelvic pain in endometriosis—a complex and often overlooked condition.

My ultimate goal through work would be to help unravel the mechanisms underlying pain and inflammation with endometriosis. This may eventually translate into better diagnostic tools and treatments. I am also drawn to bridge a gap between basic research and clinical applications in order to have an impact on the lives of patients.

Outside the lab, I enjoy listening to music and exploring different cuisines. I’m also always up for discussing innovative research ideas and new advances in health diagnostics.

For contact: samruddhi.kmcmpl2023@learner.manipal.edu

                        Richa Patel

Hi, I am Richa Patel, a doctoral student in Reproductive Science. As a biochemistry major, I gained a solid understanding in cell biology, molecular biology, immunology and advanced biotechnology methods. My current interest is to investigate the link between cellular senescence and endometriosis.

My goal is to investigate the role of cellular senescence in the pathogenesis of endometriosis and further explore therapeutic potential of senolytic drugs. I am motivated to make a major contribution for women with endometriosis by improving their quality of life.

In my spare time, I enjoy travelling and adventurous activities, watching documentaries and movies.

For contact: patel.kmcmpl2024@learner.manipal.edu

Meet our collaborators!

Dr. Rahul Gajbhiye (Scientist E)

Deputy Director

Department of Clinical Research Laboratory, ICMR-NIRRCH

Prof. Guruprasad Kalthur

Head of Department

Department of Reproductive Science, KMC, Manipal

Prof. Satish Kumar Adiga

Professor

Department of Reproductive Science, KMC, Manipal

Dr. Radhakrishna P.

Postdoctoral Scientist

University of Basel, Switzerland

Dr. Souvik Dey

Assistant Professor

Manipal Centre of Biotherapeutic Research (MCBR), MAHE Manipal

Prof. Raviraja N.S.

Head of Department

Manipal Centre of Biotherapeutic Research (MCBR), MAHE Manipal

Dr. Arnab Barik

Assistant Professor

Centre of Neuroscience, IISc, Bangalore

Dr. Swar Shah

Obstetrician Gynecologist & Laproscopic surgeon, Vadodara

Dr. Subhamoy Mandal

Assistant Professor

School of Medical Science and Technology, IIT-Kharagpur

Prof. Ganesh Venkatraman

Professor

Department of Bio-Medical Sciences, School of Bio Sciences and Technology, VIT, Vellore

Dr. Ratul Dutta

Obstetrics and Gynecology

IVF and Infertility Clinic,

down town hospital (dth), Guwahati